Ignorance is Bliss

'The most merciful thing in the world, I think, is the inability of the human mind to correlate all its contents. We live on a placid island of ignorance in the midst of black seas of infinity, and it was not meant that we should voyage far. The sciences, each straining in its own direction, have hitherto harmed us little; but some day the piecing together of dissociated knowledge will open up such terrifying vistas of reality, and of our frightful position therein, that we shall either go mad from the revelation or flee from the light into the peace and safety of a new dark age.' -- H. P. Lovecraft, The Call of Cthulhu
Kind of reminds one of the Total Perpsective Vortex from H2G2: ' ... if life is going to exist in a Universe of this size, then the one thing it cannot afford to have is a sense of proportion.' (Chapter 11 from The Restaurant at the End of the Universe)